BRIAN LAMARCHE, Ph.D. ,
Vice President of Software Engineering

Brian LaMarche is a software engineer with 20 years of experience in building field driven software applications for various scientific and research disciplines. 

He is currently the Vice President at Hecate where he directs a team an engineering team in building a predictive analytics software suite called GreenLight for the purpose of environmental compliance in the oil and gas industry.  He plays a critical role in business and new product development at Hecate including software development for biological, fisheries and environmental data.  He was part of a R&D 100 team that developed instrumentation and software to enable advanced screening techniques for finding cancerous cells.  Brian has extensive experience building real-time software applications that work in remote locations.  He has developed algorithms for analyzing large amounts of protein data using unsupervised learning methods, and developed stream processing software for processing petabytes of data into condensed searchable databases.   

Brian received his B.S. with Honors in Computer Science in 2004 from Washington State University.  He received his Doctorate in Computer Science from Washington State University Tri-Cities (WSU-TC) in 2016 for his research that was focused on the alignment and correlation of hundreds of proteomic and metabolomic datasets using unsupervised learning techniques.  

From 2011 to 2018, Brian was an adjunct professor at WSU-TC where he taught software courses to undergraduates in software design, testing, and advanced data structures.  During his tenure, he designed advanced teaching aides which integrated modern embedded hardware, including the Raspberry Pi and Arduino, into his curriculum.  He works with his local area high schools to help integrate computer science into their STEM curriculums. 

 

Experience  

  • Digital Pressure Testing  

  • Oil and Gas 

  • Environmental Software Development 

  • Acoustic Telemetry and Tracking  

  • Peptide Identification using Mass Spectrometry 

  • Unsupervised Machine Learning  

 

Certifications  

  • BOSIET 

  • OGUK 

  • SAFE Gulf / SAFE Land  

  • PEC 

  • TWIC 

 

Education Experience 

Doctorate of Philosophy 

Computer Science  

Washington State University Tri-Cities, 2016 

Dissertation Title:  Methods for Comparing Metaproteomic Data in the Absence of Metagenomic Information 

 

B.S. (with honors) 

Computer Science  

Washington State University, 2004 

 

Publications

1. Lamarche BL, KL Crowell, N Jaitly, VA Petyuk, AR Shah, AD Polpitiya, JD Sandoval, GR Kiebel, ME Monroe, SJ Callister, TO Metz, GA Anderson, and RD Smith. 2013. "MultiAlign: a multiple LC-MS analysis tool for targeted omics analysis." BMC Bioinformatics14:Article No. 49.

2. Amidan BG, DJ Orton, BL Lamarche, ME Monroe, RJ Moore, RD Smith, LH Sego, SH Payne, and MF Tardiff. 2013. "Signatures for Mass Spectrometry Data Quality." PNNL-SA-97216, Pacific Northwest National Laboratory, Richland, WA. [Unpublished – Submitted to Journal of Proteomics Research]

3. Crowell KL, GW Slysz, ES Baker, BL Lamarche, ME Monroe, YM Ibrahim, SH Payne, GA Anderson, and RD Smith. 2013. "LC-IMS-MS Feature Finder: Detecting Multidimensional Liquid Chromatography, Ion Mobility, and Mass Spectrometry Features in Complex Datasets." Bioinformatics2013 Sep 13(Epub ahead of print):

4. Crowell KL, ES Baker, SH Payne, YM Ibrahim, ME Monroe, GW Slysz, BL Lamarche, VA Petyuk, PD Piehowski, WF Danielson, III, GA Anderson, and RD Smith. 2013. "Increasing Confidence of LC-MS Identifications by Utilizing Ion Mobility Spectrometry." International Journal of Mass Spectrometry.

5. Leach FE, III, GA Anderson, RV Norheim, RJ Ewing, BL Lamarche, JH Futrell, YM Ibrahim, RD Smith, EW Robinson, DW Koppenaal, AV Tolmachev, IK Webb, TY Lin, and L Pasa-Tolic. 2013. "PROGRESS TOWARDS ENHANCED HIGH FIELD FT-ICR MS AT EMSL." Presented by Franklin E. Leach III (Invited Speaker) at 9th North American FTMS Conference, Key West, FL, FL on April 30, 2013.

6. Lamarche BL, KL Crowell, SH Payne, VA Petyuk, ME Monroe, SJ Callister, TO Metz, J Miller, RR Lewis, GA Anderson, and RD Smith. 2013. "MultiAlign- a scalable and flexible infrastructure for label-free quantitation." Presented by Brian LaMarche at Cascadia Proteomics Symposium, Seattle, WA on July 15, 2013.

7. Kim JA, KJ Auberry, BL Lamarche, CM Woodley, GR Ploskey, and MA Weiland. 2013. "Form, Function and Structuring Large Multi-year Database of Acoustic Monitoring (MyDAM)." Presented by Jina Kim at International Conference on Engineering and Ecohydrology for Fish Passage, Corvallis, OR on June 26, 2013.

8. Woodley CM, AR Phillips, BL Lamarche, NG Trimble, and MA Weiland. 2013. "FishSuite! Software for annotating, photographing, tracking, and reporting on fish and physiological condition." Presented by Mark A. Weiland at International Conference on Engineering and Ecohydrology for Fish Passage, Corvallis, OR on June 27, 2013.

9. Lamarche BL, MA Weiland, CM Woodley, EY Choi, AE Flory, NG Trimble, AR Phillips, DA Parrs, AI Thronas, MC Richart, KJ Auberry, and MB Eppard. 2012. "A Fisheries Information Management System for Petabyte Scale Telemetry." Presented by Brian LaMarche at 142nd Annual Meeting of the American Fisheries Society, Minneapolis-St. Paul, MN on August 22, 2012.

10. Trimble NG, AR Phillips, CM Woodley, BL Lamarche, and MA Weiland. 2012. "FishSuite - Software for Annotating, Photographing, Tracking, and Reporting on Physiological Condition for Telemetry Related Studies." Presented by Nathan Trimble at 142nd Annual Meeting of the American Fisheries Society, St. Paul, MN on August 20, 2012.

11. Weiland MA, Z Deng, TA Seim, BL Lamarche, EY Choi, T Fu, TJ Carlson, AI Thronas, and MB Eppard. 2011. "A cabled acoustic telemetry system for detecting and tracking juvenile salmon: Part 1. Engineering design and instrumentation." Sensors 11(6):5645-5660.

12. Deng Z, MA Weiland, T Fu, TA Seimstrong BL Lamarche, EY Choi, TJ Carlson, and MB Eppard. 2011. "A Cabled Acoustic Telemetry System for Detecting and Tracking Juvenile Salmon: Part 2. Three-Dimensional Tracking and Passage Outcomes." Sensors 11(6):5661-5676.

13. Baker ES, EA Livesay, DJ Orton, RJ Moore, WF Danielson, DC Prior, YM Ibrahim, BL Lamarche, AM Mayampurath, AA Schepmoes, DF Hopkins, K Tang, RD Smith, and ME Belov. 2010. "An LC-IMS-MS Platform Providing Increased Proteome Coverage for High-Throughput Studies." Journal of Proteome Research 9(2):997-1006

14. Marginean I, RT Kelly, RJ Moore, DC Prior, BL Lamarche, K Tang, and RD Smith. 2009. "Selection of the Optimum Electrospray Voltage for Gradient Elution LC-MS Measurements." Journal of the American Society for Mass Spectrometry 20(4):682-688

15. Lamarche BL, RR Lewis, DC Girvin, and JP McKinley. 2008. "Automated Classification of Scanning Electron Microscope Particle Images using Morphological Analysis." Presented by Brian La Marche at American Geophysical Union Annual Meeting, San Francisco, CA on December 18, 2008.

16. Livesay EA, K Tang, BK Taylor, MA Buschbach, DF Hopkins, BL Lamarche, R Zhao, Y Shen, D Orton, RJ Moore, RT Kelly, HR Udseth, and RD Smith. 2008. "Fully automated four-column capillary LC-MS system for maximizing throughput in proteomic analyses." Analytical Chemistry 80(1):294-302

17. Petyuk VA, MH Chin, W Qian, RJ Moore, HM Brewer, DJ Orton, EA Livesay, ME Monroe, JN Adkins, BL Lamarche, DG Camp, II, DJ Smith, and RD Smith. 2007. "A Novel Approach for Multiplex Imaging of Protein Abundances in Tissues and Organs: Initial Application to the Mouse Brain." Presented by Vladislav A. Petyuk at The Eighth International Conference on Systems Biology on October 1, 2007

18. Lamarche BL, DF Hopkins, CO Hughes, TP McKenna, and EW Fulp. 2007. "A Network Layer for Teleoperations in High Speed Environments." Presented by Errin W. Fulp (Invited Speaker) at IEEE INFOCOM 2007 High-Speed Networks Workshop, Anchorage, AK on May 11, 2007

19. Perrine KA, BL Lamarche, DF Hopkins, SE Budge, L Opresko, HS Wiley, and MB Sowa. 2007. "High Speed Method for in Situ Multispectral Image Registration." Microscopy Research and Technique 70(4):382-389. doi:10.1002/jemt.20423

20. Perrine, K., Hopkins, D. F., LaMarche, B., and Sowa, M. B., Getting the Pixels in Line: A Real-time Image Processing System for Biology, Scientific Computing, October, 16-20 (2005).

Brian LaMarche, VPSD, Ph.D.